What is Phellodendron extract?
A proprietary formulation consisting of a Phellodendron amurense (Amur cork tree) bark extract, often used in traditional Chinese medicine, with anti-inflammatory, anti-oxidant and potential chemopreventive and antineoplastic activities. Medicinal use Used orally to treat abdominal pain, diarrhea, gastroenteritis and urinary tract infections. Phellodendron amurense may protect cartilage against osteoarthritis progression. It may prove to be a potentially important chemopreventive agent for lung cancer.
What is the common name for Phellodendron?
Common names: Amur cork tree. Scientific names: Phellodendron amurense. The Amur corktree is an important and beautiful tree native to several parts of Asia. Its scientific name is Phellodendron amurense. Phello” in Greek means “cork” and “dendron” means tree, which yield its common name. Amur is a province in mainland China, which gives the corktree its common name.
Is Phellodendron the same as berberine?
Phellodendron contains a chemical called berberine. Berberine might lower blood sugar levels. Taking phellodendron along with diabetes medications might cause blood sugar to drop too low. Berberine does not produce instant results, and most studies that observed positive weight loss lasted approximately three months. Findings from an older 2012 study showed similar results—participants who took 500mg of berberine three times per day experienced weight loss results after twelve weeks.How long does it take for weight loss on berberine? Berberine works gradually in your system. You may see modest weight changes after taking it consistently for at least 8 weeks, together with a balanced diet and regular physical activity.Phellodendron amurense is a plant whose alkaloid, berberine, has been shown to reduce leptin and glycerol secretion in adipocytes and may decrease the expression of inflammatory molecules secreted by these cells.Additionally, a review of 12 studies found that supplementing with berberine led to significant reductions in body weight, body mass index, and belly fat. It also decreased levels of C-reactive protein, a marker of inflammation ( 15 ).
Who should avoid berberine?
People who are pregnant or breastfeeding should not use berberine, and it should not be given to infants. Berberine can cause or worsen jaundice in newborn infants and could lead to a life-threatening problem called kernicterus. Berberine might also interact with medicines in negative ways. When taken by mouth: Berberine is possibly safe for most adults. It’s been used safely in doses up to 1. Common side effects include diarrhea, constipation, gas, and upset stomach. When applied to the skin: Berberine is possibly safe for most adults when used short-term.Berberine improves lipid metabolism in the liver through several mechanisms. One such mechanism involves the upregulation of microsomal triglyceride transfer protein [39], promoting the release of TG from liver cells into the bloodstream. This reduces TG accumulation in hepatocytes and alleviates hepatic steatosis.Is berberine bad for your kidneys? A recent study found that berberine could have a positive effect on people with kidney problems. It works by affecting the bacteria in your gut and stopping the production of harmful gut substances that can worsen kidney disease.The berberine in phellodendron might lower blood sugar and cholesterol levels, as well as protect the liver. But berberine can also be harmful. People use phellodendron for acne, diabetes, obesity, osteoarthritis, stress, and many other conditions, but there is no good scientific evidence to support these uses.Berberine is a substance found in a variety of plants, including goldenseal, barberry, Oregon grape, and others. Plants containing berberine have a long history of use in both Ayurvedic and Chinese medicine.