Is Andrographis paniculata safe?
Key messages. Medicines containing the herb Andrographis paniculata (andrographis) may cause allergic reactions – which can include life-threatening anaphylaxis – in some people. Severe allergic reactions have been reported to occur in people who had used the product previously without any reaction. Andrographolide, a diterpenoid component found in traditional Chinese medicine Andrographis paniculata, is known as a natural antibiotic and can be used to treat inflammatory lesions of various systemic diseases.People commonly use andrographis for the common cold, osteoarthritis, infection of the throat and tonsils, and a type of bowel disease called ulcerative colitis. It is also used for many other conditions, but there is no good scientific evidence to support its other uses.Double-blind trials have shown that common cold symptoms improve and recovery is faster when andrographis extract containing 48 to 60 mg andrographolides is taken in three or four divided doses daily, beginning as soon as possible after symptoms appear.
What are the benefits of Andrographis paniculata?
Laboratory studies and studies on humans suggest that Andrographis may act against infections and viruses, and relieve diarrhoea, fever and pain. Andrographis has been used in combination with other herbs for up to one month. Pregnancy and breast-feeding: Andrographis is POSSIBLY UNSAFE when taken by mouth during pregnancy. There is a concern that it might cause miscarriages. Not enough is known about the safety of andrographis during breast-feeding.Andrographis is LIKELY SAFE when taken by mouth appropriately, short-term. It also appears to be safe when taken as a specific combination product containing andrographis extract and Siberian ginseng (Kan Jang, Swedish Herbal Institute) for up to 3 months.
What are the side effects of Andrographis paniculata?
Some people develop intestinal upset when taking andrographis. If this occurs, reduce the amount taken or take it with meals. Headache, fatigue, a bitter/metallic taste, and elevated liver enzymes were reported in one trial with HIV-infected people taking high doses of isolated andrographolides. Adverse Reactions In a clinical trial, headache, fatigue, rash, bitter/metallic taste, diarrhea, pruritus, and decreased sex drive were reported with andrographis 10 mg/kg body weight.
Is Andrographis paniculata good for diabetics?
Andrographis paniculata (Burm. Nees plant originates from India, and has been used for several purposes, primarily preventing diabetes mellitus (DM). Ethanolic extracts of this plant can decrease the blood glucose levels in type 1 DM rats. Andrographolide (AP) is one of the main active ingredients of Herba Andrographitis. It has several biological activities and has been reported to have protective and therapeutic effects against liver diseases.
Is andrographis good for lungs?
Andrographis paniculata is a medicinal herb cultivated in South Asia. In the United States, supplements made from this herb are used to relieve respiratory infections and inflammatory conditions. Andrographis supplements are made from the active part of the andrographis herb, called andrographolide. Plants have been historically utilized to heal various ailments, and Andrographis paniculata is one of them, with antibacterial and antioxidant activities. A. Acanthaceae and is commonly known as the ‘king of bitterness’ [1].
Is andrographis good for your liver?
Andrographolide (AP) is one of the main active ingredients of Herba Andrographitis. It has several biological activities and has been reported to have protective and therapeutic effects against liver diseases. Preliminary studies in animals weakly suggest that andrographis may also offer benefits for preventing heart disease. In addition, highly preliminary studies suggest that andrographis may help protect the liver from toxic injury, perhaps more successfully than the better-known milk thistle, a liver-protective herb.