What is glycyrrhiza inflata root extract?
Glycyrrhiza inflata, commonly known as Chinese licorice, has been esteemed in traditional medicine for its therapeutic properties. The root extract is particularly valued in skincare for its high concentration of Licochalcone A, a potent flavonoid with notable anti-inflammatory and antioxidant activities. Licorice root can raise blood pressure and interact with certain medications. Even small amounts of glycyrrhizin—the active compound—may cause side effects, especially in people with heart or kidney problems.Licorice root has been used for thousands of years to help treat a variety of ailments, including respiratory conditions and digestive distress.Experts point out that licorice root contains “glycyrrhizin” — a set of compounds that can alleviate liver toxicity. Notably, licorice can reduce the risk of liver cancer in people with hepatitis C. Researchers suggest that licorice root may be a powerful antioxidative, giving it its liver-protective properties.The root of the licorice plant has been used medicinally for thousands of years. Chinese medicine has long used licorice root to treat many ailments, including gastrointestinal problems, malaria, insomnia, and infections. Licorice root is often used as a sweetener in beverages, candy, and medicine.Even small amounts of glycyrrhizin from licorice root products have been linked to severe adverse effects in people who consume a lot of salt, in people with hypertension, and in people with heart or kidney conditions.
What is glycyrrhiza used for?
Glycyrrhiza glabra (family Fabaceae), commonly known as licorice, is an herbaceous perennial and has been used as a flavoring agent in foods and medicinal remedies for thousands of years. Licorice root has been widely used around the world to treat cough since ancient times. Liquorice comes from the root of a plant called glycyrrhiza glabra. The root extract has a sweet flavour, and contains over 300 different active compounds. Studies show that liquorice may be effective for a number of conditions, including indigestion, hot flushes and low blood pressure.Licorice that contains glycyrrhizin is possibly unsafe when consumed in large amounts or for a long time. Eating licorice 5 grams or more daily for several weeks can cause severe side effects including heart attack. People who have heart disease, kidney disease, or high blood pressure are more sensitive to it.Glycyrrhiza (Licorice or GanCao) is a renowned traditional herb with a history over 2000 years, acclaimed for its function of “ counteracting all poisons”, as documented in Chinese Pharmacopeia [16], and its active flavonoids components exhibit diverse neuropharmacological activities including antidepressant, .The most widely reported side effect of glycyrrhizin use via consumption of black liquorice is reduction of blood potassium levels, which can affect body fluid balance and function of nerves.
What is Glycyrrhiza used for?
Glycyrrhiza glabra (family Fabaceae), commonly known as licorice, is an herbaceous perennial and has been used as a flavoring agent in foods and medicinal remedies for thousands of years. Licorice root has been widely used around the world to treat cough since ancient times. While licorice root shows promise in treating skin conditions, GERD, peptic ulcers, and may have anticancer properties, further research is needed to confirm these benefits. Both chronic use and large doses of licorice root may lead to glycyrrhizin accumulation in the body, which may cause side effects.
What are the benefits of glycyrrhizin?
Glycyrrhizin is what makes licorice taste sweet, and it has been linked to many pharmacological and biological benefits. Glycyrrhizic acid inhibits elevated cortisol levels, the production of proinflammatory cytokines such as tumor necrosis factor-a, interleukin-1a, -1b, and -6, and prostaglandin E2. Moreover, licorice extract markedly decreases the biochemical and histopathologic changes in AP, preserving the pancreatic and lung tissues through its antioxidant, anti-inflammatory, and antiapoptotic effects.
How much glycyrrhizin is safe per day?
Safety Summary Licorice is generally well tolerated with occasional use or when glycyrrhizin dosage is kept below 100 mg daily. Long-term consumption of moderate to large amounts of licorice can cause pseudohyperaldosteronism. Symptoms may include increased blood pressure, low potassium, and water retention. However, it is known that eating licorice can also raise blood pressure. This is mainly due to a substance called glycyrrhizic acid that affects the body’s fluid balance through effects on an enzyme in the kidney. High blood pressure, in turn, increases the risk of cardiovascular disease.Even small amounts of glycyrrhizin from licorice root products have been linked to severe adverse effects in people who consume a lot of salt, in people with hypertension, and in people with heart or kidney conditions.Adverse Effects of Licorice Increased potassium excretion can be a particular problem for people who have heart disease and for those who take digoxin or diuretics that also increase potassium excretion. Such people and those who have high blood pressure should avoid taking licorice.