What is Polygala tenuifolia used for?
The root of Polygala tenuifolia Willdenow has been used for the treatment of insomnia, depression, and amnesia. It is known for its ability to nourish the liver and kidneys, strengthen tendons and bones, and enhance cognitive function while calming the nerves. Modern pharmacological research has shown that Polygala tenuifolia contains various components that can inhibit the formation of beta-amyloid proteins in the brain.
What is another name for Polygala tenuifolia?
Polygala tenuifolia (PT), also called Yuanzhi by the ancients, is another traditional Chinese herb frequently used for insomnia treatment. Polygala tenuifolia (yuǎn zhì; Chinese: 远志) is an herb in the family Polygalaceae which is hardy to USDA Zone 6.
What neurotransmitters are in Polygala tenuifolia?
Some preclinical studies indicate that extracts from Polygala tenuifolia may influence neurotransmitter levels, including acetylcholine, dopamine, and serotonin, primarily in animal models. The proposed mechanisms involve antioxidant effects, inhibition of acetylcholinesterase, and modulation of neuroinflammation. Polygala tenuifolia and its active components have multiplex neuroprotective potential associated with AD, such as anti-Aβ aggregation, anti-Tau protein, anti-inflammation, antioxidant, anti-neuronal apoptosis, enhancing central cholinergic system and promote neuronal proliferation.