What is Silybum marianum extract?
Silybum Marianum Extract description In short, it’s an impressive antioxidant to see in skin care products, particularly those that address environmental stressors. Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Silymarin is the extract of Silybum marianum, or milk thistle, and consists of seven flavonoglignans (silibinin, isosilibinin, silychristin, isosilychristin and silydianin) and a flavonoid (taxifolin) [3]. Among these substances, silybin is mainly prevalent and has the most important biological effect.
What is the best time to take silymarin?
Some general guidelines suggest that taking silymarin with meals, particularly with food that contains some fat, can enhance its absorption and bioavailability. Additionally, some individuals may find it helpful to take silymarin in the morning or evening, depending on their personal preferences and schedules. Featured. Medical research on milk thistle and liver health has led to mixed results. Studies show that silymarin may help ease inflammation and promote cell repair. This may help ease symptoms from liver diseases like jaundice, cirrhosis, liver cancer, and fatty liver disease.Silymarin has besides antifibrotic, immunomodulating, anti-inflammatory effects as well as antioxidant properties by scavenging free radicals and increasing the glutathione concentrations, so that it can be used in hepatitis and hepatic cirrhosis treatment and in mushroom poisoning (5, 7,10).TNF-α was also reduced after silymarin therapy, as a consequence of the anti-inflammatory action of the drug. This clearly demonstrated a reduction of the hepatic inflammation. Finally, the changes of hepatorenal brightness index clearly demonstrated the reduction of hepatic fat accumulation after silymarin therapy.Recent evidence suggests that silymarin may be just as important for kidney health as for liver. Silymarin concentrates in kidney cells, where it aids in repairing and regeneration by increasing protein and nucleic acid synthesis.
What are the side effects of Silybum marianum?
Adverse effects associated with oral ingestion of milk thistle include: Gastrointestinal problems (e. Headache. If you have breast cancer, uterine cancer, ovarian cancer, endometriosis or uterine fibroids, consider avoiding milk thistle. Milk thistle can cause an allergic reaction, including a severe, potentially life-threatening allergic reaction (anaphylaxis).In conclusion, milk thistle is an effective treatment for liver and kidney diseases due to its antioxidant, anti-inflammatory, regenerative, and protective properties.There are few side effects to taking milk thistle, however some people have reported experiencing nausea and bloating. WebMD reports that people who are allergic to certain plants such as artichokes, ragweed, daisies and chrysanthemums are more likely to also be allergic to milk thistle.There’s evidence that milk thistle might help lower cholesterol and lower the risk of heart disease. However, those results came from studies of people with diabetes, so it’s unclear if people without diabetes would experience the same benefits.