What is Picralima nitida used for?
Picralima nitida is a therapeutic herb used in ethnomedicine for the management of several disease conditions including diabetes. Akuammine (1) and pseudo-akuammigine (2) are indole alkaloids found in the seeds of the akuamma tree (Picralima nitida). Both alkaloids are weak agonists of the mu opioid receptor (μOR); however, they produce minimal effects in animal models of antinociception.The seeds of the akuamma tree (Picralima nitida) have been used as a traditional treatment for pain and fever.