May 2026

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Which medicine is best for a cold and runny nose?

Which medicine is best for a cold and runny nose? Cold Medicines for Runny Nose, Watery Eyes, and Sneezing Over-the-counter antihistamines, such as chlorpheniramine and diphenhydramine, may relieve these cold symptoms for one or two days, experts say. A combination of antihistamines and decongestants may work better. When are painkillers helpful? Painkillers like acetylsalicylic acid

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